Table 6: Antipruritic and Anti-inflammatory Medications for Cats
Download a PDF of Table 6
| Drug Name | Cyclosporine1 | Glucocorticoids2 |
|---|---|---|
| Mode of action | Calcineurin inhibitor that modulates T-cell function | Influences gene expression of proinflammatory cytokines |
| Administration | PO
q 24 hr |
PO
Injectable not recommended |
| Time to onset | 4–6 wk | Hours |
| Age | >6 mo | Any |
| Weight | >1.4 kg | Any |
| Health restrictions | History of neoplasia Renal insufficiency |
Congestive heart failure Diabetes mellitus Hyperadrenocorticism Hypertension |
| Adverse reactions | Vomiting Diarrhea Gingival hyperplasia Hypersalivation Lethargy Drug interactions |
Polyuria/polydipsia Polyphagia Diabetes mellitus Obesity Muscle wasting Iatrogenic hyperadrenocorticism Congestive heart failure |
PO, orally; SC, subcutaneously.
- Atopica for Cats (cyclosporine oral solution). Package insert. Elanco.
- Plumb DC. Plumb’s Veterinary Drug Handbook. 9th ed. Wiley-Blackwell;2018.
Note: Oclacitinib is not labeled for use in cats. Lokivetmab is contraindicated in cats.
The 2023 AAHA Management of Allergic Skin Diseases in Dogs and Cats Guidelines are generously supported by Hill’s Pet Nutrition, Merck Animal Health, and Zoetis.
