Table 3: Oral Antihistamine Doses for Dogs
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Drug Name |
Dose |
---|---|
Hydroxyzine |
2 mg/kg q 12 hr1 |
Cetirizine |
1–2 mg/kg q 24 hr1 |
Chlorpheniramine |
0.4 mg/kg q 12 hr2 |
Cyproheptadine |
0.3–2 mg/kg q 12 hr2 |
Clemastine |
0.05–1 mg/kg q 12 hr2 |
Loratadine |
1 mg/kg q 12 hr2 |
Fexofenadine |
5–15 mg/kg q 24 hr3 |
Amitriptyline |
1–2 mg/kg q 12 hr2 |
Diphenhydramine |
2–3 mg/kg q 12 hr2 |
- Bizikova P, Papich MG, Olivry T. Hydroxyzine and cetirizine pharmacokinetics and pharmacodynamics after oral and intravenous administration of hydroxyzine to healthy dogs. Vet Dermatol. 2008;19:348–57.
- Miller WH, Griffin GE, Campbell KL. Muller & Kirk’s Small Animal Dermatology. 7th ed. St. Louis:Elsevier;2013.
- Plevnik A, Kobal S, Domanjko-Petric A, et al. The efficacy of antihistamine fexofenadine versus methylprednisolone in the treatment of atopic dermatitis in dogs. Slov Vet Res. 2009;46:5–12.
- Banovic F, Denley T, Blubaugh A, et al. Effect of diphenhydramine and cetirizine on immediate and late-phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study. Vet Dermatol. 2020;31:256–e58.